NeoLife: Decades of Excellence

NeoLife: Decades of Excellence

By John Miller,
SAB Director, Product Technologist, Researcher

When I was asked to write this blog, I was excited to embark on the project. After all, I had a front row seat from
which to observe it for 55 years. How much fun that will be, I thought.

Being an analytical type, I started by first thinking about what the word “excellent” represents. Dictionary definitions
are always pretty good references. I chose Webster’s New World College Dictionary: “Excellent, adjective;
Outstandingly good of its kind; of exceptional merit, virtue, etc.” No surprise there.

Though NeoLife as a company, and our products, easily fulfill that definition, I felt it lacks the perspective of time.
It’s one thing to do something excellently once. It’s a much bigger thing to do it repeatedly. Excellence is not a
static attribute. It is transitory. What was considered excellent in 1973 could be quite different from what is
considered excellent today. Nowhere is that reality better displayed than our products and the science and technology
that support them.

Let’s take a quick look back along the NeoLife excellence timeline and I think you’ll see what I mean.

Excellence from Day One:

When NeoLife started business back in 1958 it focused on the idea that health-eroding dietary deficiencies were
widespread, and supplementation was a powerful way to fix that. An excellent, intuitively smart idea that has stood the
test of time.

The product the company started with, what we call Formula IV today, is where the excellence of that moment is found.
Including a broad array of vitamins and mineral and related nutritional factors made it a great choice. But with the
inclusion of cell-building “lipids and sterols” a new standard of product excellence was established, Cellular
Nutrition. One that science has substantiated repeatedly over the decades since. Looking back on that from today’s
perspective it seems obvious that viewing nutritional needs through the lens of the cell was an excellent idea that has
stood the test of time.

Acknowledging and Delivering the Power of Whole Food.

By the 1960s supplement companies were starting to become a more visible part of day-to-day life. Big companies brought
big dollars to the marketplace, and with them, large scale production of vitamins and minerals for supplementation or
food fortification. Strong advertising campaigns about the benefits that they would provide began to get consumer

Fully aware of this situation, NeoLife took a more cautious and prudent course. Did it make sense that such highly
refined and isolated nutrients alone would address the nutritional health challenge? To answer that question, they
looked to the best reference point there was, Mother Nature. What was Nature’s Plan for Human Nutrition? And Nature
pointed the way.

In the middle 1960s NeoLife introduced the product we call Neo-C; a great-tasting chewable vitamin C. During development, by
“following Nature’s Blueprint” NeoLife formulators discovered that Nature never delivers vitamin C all by itself. It is
always accompanied by other related food factors.

Using the whole orange as their model NeoLife researchers first identified and then included those whole citrus factors
in Neo-C, establishing a new standard of excellence for vitamin C supplementation. This Nature’s Blueprint philosophy is
still alive and well in our product line some 50+ years later as NeoPlex Concentrate.

Over the subsequent decades, science has shown that the presence of these nutritional factors in citrus can amplify the
benefits of vitamin C in the body for better absorption and better retention.1 An often-overlooked example of
NeoLife foresight that has stood the test of time.

Others Recognise NeoLife Excellence.

Moving forward on the excellence timeline a couple of decades or so brings us to the early 1990s. Though many moments of
excellence populate that period, the 1990s reflect a new standard of excellence that separated NeoLife from the rest of
the industry. While continuing our commitment to “follow Nature’s blueprint” and tapping into vast amounts of data
resulting from access to the United States Department of Agriculture’s (USDA) NHANES (National Health and Nutrition
Examination Survey) database, the NeoLife Scientific Advisory Board (SAB) triggered a long, connected period of product
excellence that remains unmatched today. This work got the attention of, and acceptance from, scientists and researchers
across the health and disease research spectrum.

From years of research and development to identify, extract and deliver highly sensitive bioactive whole food components
Carotenoid Complex was born. That story is one of the greatest in the supplement industry and would take way too long to
tell here. But the series of events that came from that tell an unmatched story of excellence.

It starts with our human clinical bioavailability study. Pretty much unheard of before for dietary supplements, the
NeoLife SAB produced evidence that highly sensitive bioactive components of whole foods called “carotenoids” could be
extracted, packaged in a gelatin capsule delivery system, and delivered intact in the blood stream. Powerful data!

NeoLife Excellence Gets Attention:

Awareness of our work on carotenoids got the attention of researchers from across the country and resulted in the SAB
receiving an invitation to a special meeting of the New York Academy of Sciences (NYAS) called “Carotenoids in Human
Health.” The abstract of that work was published in the Annals of the NYAS in 1993.2

While this was happening, the entire study was presented for publication to The American Journal of Clinical Nutrition,
one of the world’s most prestigious peer-reviewed journals. Acknowledging the excellence and timeliness of that work, it
was accepted and published in April 1994.3

Meanwhile, sitting in the audience at the NYAS event were members of the USDA’s Human Nutrition Research Centers.
Shortly after that meeting, they approached us with the idea of doing some additional research on Carotenoid Complex as
part of their work on understanding benefits and determining recommended intakes for carotenoids from food. Another
indication of the excellence the product represented. After short discussion and consideration by the SAB, we agreed.

Third Party Proof of Excellence:

Following our agreement those USDA researchers embarked on a series of studies that established the excellence of
Carotenoid Complex beyond a doubt. Over the next few years, they, along with the SAB, presented and published
peer-reviewed evidence that reconfirmed bioavailability and showcased its beneficial bioactivity in the blood
stream4, on cell membranes5-6 and within the healthy immune system.7-8 That work, as
well as subsequent work done by the SAB and others, has made Carotenoid Complex one of the most tested and validated
product of its kind. Excellence only NeoLife has achieved.

NeoLife Excellence; Standing the Test of Time.

Whether you look at the excellence of the Formula IV of 1958, or the introduction of whole citrus fortified Neo-C in the
60s, or the compelling excellence of Carotenoid Complex and its amazing scientific proof of benefit, these are all just
reflections of the genesis and perpetuation of excellence fostered by and drawn from the company’s commitment to that
goal. It can be seen throughout our product line. Every product is grounded in the pursuit of excellence… and of course
with an undying respect for Nature’s plan.

There are many examples of NeoLife product excellence in our 65-year history. Far too many to cover here. It is my hope
that this gives you some insight into the excellence that is NeoLife.

Check Out

Formula IV

First multifactor food supplement to provide vitamins and related food factors, minerals and
enzymes, and lipids and sterols.

Formula IV

Neo-C Chewable

Neo-C Chewable

Chewable vitamin C with the equivalent of 4 oranges in each tablet to support immunity.

Carotenoid Complex

Exclusive blend of broad spectrum, powerful, immune-boosting carotenoid nutrients from fruits and

Carotenoid Complex



  1. Vinson JA, Bose P. Comparative bioavailability to humans of ascorbic acid alone or in a
    citrus extract. Am J Clin Nutr. 1988 Sep; 48(3): 601-4.
  2. Carughi A, Hooper FG. Plasma carotenoid concentrations before and after supplementation
    with a carotenoid mixture. Ann N Y Acad Sci. 1993; 691: 244-45.
  3. Carughi A, Hooper FG. Plasma carotenoid concentrations before and after supplementation
    with a carotenoid mixture. Am J Clin Nutr. 1994 Apr; 59(4): 896-9.
  4. Dixon ZR, et al. Effects of a carotene-deficient diet on measures of oxidative
    susceptibility and superoxide dismutase activity in adult women. Free Radic Biol Medicine. 1994 Dec;
    17(6): 537-44.
  5. Dixon ZR, et al. Effect of low carotene diet on malondialdehyde (MDA) concentration.
    FASEB J; 1996; 10: A240.
  6. Dixon ZR, et al. The effect of a low carotenoid diet on malondialdehyde-thiobarbituric
    acid (MDA-TBA) concentrations in women: a placebo-controlled double-blind study. J Am Coll Nutr. 1998
    Feb; 17(1): 54-8.
  7. Kramer TR, Burri BJ, Neidlinger TR. Carotenoid/Flavonoid Modulated Immune Response in
    Women. Proceedings of the annual meeting of Professional Research Scientists Federation of American Societies of
    Experimental Biology. April 9-13, 1995. San Francisco, California.
  8. Kramer TR, Burri BJ. Modulated mitogenic proliferative responsiveness of lymphocytes in
    whole-blood cultures after a low-carotene diet and mixed-carotenoid supplementation in women. Am J Clin
    . 1997 Mar; 65(3): 871-5.